Associate Director for Cell and Gene Therapy, Oncology Center of Excellence (OCE), Office of the Commissioner, and Chief of Oncology Branch, Office of Tissues and Advanced Therapies, Center for Biologics Evaluation and Research (CBER), U.S. Food and Drug Administration (FDA).
Dr. Liu supervises clinical oncology review for cancer therapeutics such as chimeric antigen receptor (CAR) T-cells, dendritic cells, adoptive T cell therapies, tumor neoantigen-based personalized medicine (vaccine or cell therapy), natural killer cells, oncolytic viruses, therapeutic cancer vaccines, microbiome-based therapies and combinations of these immune-oncologic therapeutics with checkpoint inhibitors and other agents.
Liu is a medical oncologist and internist, certified by the American Board of Internal Medicine (ABIM). He received his M.D. from Henan Medical University and his PhD in Molecular Biology from Cornell University Graduate School of Medical Sciences in New York City, NY. He completed his Internal Medicine internship and residency training in Albert Einstein College of Medicine (Long Island campus) in New York City and his Medical Oncology fellowship training at the U.S. National Cancer Institute (NCI). He also received his cancer immunotherapy training in the Surgery Branch, NCI. During his fellowship, he served as associate investigators for multiple Phase 1 and 2 clinical trials investigating a variety of new cancer therapeutics. In particular, he served as protocol chairperson and was responsible for developing and conducting a Phase 1/2 clinical trial using genetically modified cells for the treatment of patients with cancer. His primary academic interests include clinical trial design, immunotherapy, cellular and gene therapies for cancer.
In 2003, Dr. Liu joined CBER as a Medical Officer / Clinical Reviewer and later was selected as a Lead Medical Officer. From 2008 to 2011, he served as a Lead Medical Officer in U.S. FDA’s Center for Drugs Evaluation and Research (CDER). He has received multiple citations at the FDA and Center levels for his contributions to the regulatory science / research / policy, product review and approval, and staff mentoring. In June 2019, he was selected to serve as Associate Director for Cell and Gene Therapy, the position he had held in an acting capacity since March 2017, for the newly created FDA’s Oncology Center of Excellence.